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2014 ACMT Scientific Symposium, NACCT

Frontiers in Pain Pharmacotherapy

October 21, 2014, 7:30-9:00am

Cummins2.jpgTheodore R. Cummins, PhD

Professor of Pharmacology and Toxicology
Stark Neurosciences Research Institute
Indiana University
Indianapolis, IN

Beyond the Mu Receptor: Ion Channels and Their Role in Pain Syndromes

Objectives:
  • Review the current knowledge regarding the roles of sodium, calcium and potassium ion channels in pain signaling.
  • Discuss the recent insights that have been gained from studying inherited pain syndromes.
  • Review the advantages and disadvantages of available drugs and describe new compounds in clinical trials that target these channels.

Sodium Channel Toxins: Poisons That Hold Promise for Developing Novel Therapies for Pain Management

Objectives: 
  • Review the mechanisms of action of insecticides, cancer chemotherapeutics and biological toxins that induce pain and paresthesias.
  • Discuss the promise that biological toxins provide in the pursuit of developing targeted sodium channel therapies for pain management.