2014 ACMT Scientific Symposium, NACCT
Frontiers in Pain Pharmacotherapy
October 21, 2014, 7:30-9:00am
Theodore R. Cummins, PhD
Professor of Pharmacology and Toxicology
Stark Neurosciences Research Institute
Indiana University
Indianapolis, IN
Beyond the Mu Receptor: Ion Channels and Their Role in Pain Syndromes
Objectives:
- Review the current knowledge regarding the roles of sodium, calcium and potassium ion channels in pain signaling.
- Discuss the recent insights that have been gained from studying inherited pain syndromes.
- Review the advantages and disadvantages of available drugs and describe new compounds in clinical trials that target these channels.
Sodium Channel Toxins: Poisons That Hold Promise for Developing Novel Therapies for Pain Management
Objectives:
- Review the mechanisms of action of insecticides, cancer chemotherapeutics and biological toxins that induce pain and paresthesias.
- Discuss the promise that biological toxins provide in the pursuit of developing targeted sodium channel therapies for pain management.