PEHSU Journal Club Webinar Series

This in-depth and interactive series provides a platform for learning and discussion about issues that focus on current and emerging aspects of pediatric and reproductive environmental health.

Endocrine Disruptors

The presenter will begin by describing the study methodologies used in the journal articles to be discussed. This will be followed by a discussion of the results of the studies under consideration and implications for current clinical and public health practice. The presenter will conclude by discussing preventive steps that can be taken to decrease exposure to endocrine disruptors as evidenced in the journal articles.

Articles to be discussed:

1. First trimester phthalate exposure and anogenital distance in newborns.
Swan SH et al.
Hum Reprod. 2015 Apr;30(4):963-72.

2. Is Hypospadias Associated with Prenatal Exposure to Endocrine Disruptors? A French Collaborative Controlled Study of a Cohort of 300 Consecutive Children Without Genetic Defect.
Kalfa N et al.
Eur Urol. 2015 May 23. pii: S0302-2838(15)00409-1. doi: 10.1016/j.eururo.2015.05.008. [Epub ahead of print]

3. Exposure to select phthalates and phenols through use of personal care products among Californian adults and their children.
Philippat C, Bennett D, Calafat AM, Picciotto IH
Environ Res. 2015 Apr 27;140:369-376.

Download Slides Here (click)

Learning Objectives

By the end of this module, participants should be able to:
  • Describe the biological effect of endocrine disrupting chemicals and their impact on reproductive and pediatric development.
  • Discuss the nature and extent of exposure to endocrine disrupting chemicals among at-risk groups.
  • Describe appropriate preventive steps to decrease exposure to endocrine disrupting chemicals.
Timur Duranni, MD, MPH, MBA and Marya Zlatnik, MD
Durranni_TimurTimur S. Durrani, MD, MPH, MBA
Co-Director PEHSU Western States
University of California San Francisco
San Francisco, CA

Dr. Timur S. Durrani is a Clinical Instructor of Medicine at the University of California San Francisco, where he holds appointments in the Department of Medicine, Division of Clinical Pharmacology and Experimental Therapeutics and Department of Family Medicine. Dr. Durrani earned his Medical Degree from the University of Arizona, where he also earned his Master of Public Health. He holds dual board certifications in Family Medicine and Preventive Medicine, and is a graduate of the UCSF Occupational and Environmental Medicine Residency and the UCSF Medical Toxicology Fellowship. His academic responsibilities include teaching medical and pharmacy students, as well as graduate medical trainees including Emergency Medicine, Occupational and Environmental Medicine residents, and Medical Toxicology Fellows. As a consultant for the Medical Toxicology Service, he provides clinical care for acutely poisoned patients at the San Francisco General Hospital, as well as outpatient Medical Toxicology consultations through the UCSF Occupational and Environmental Medicine Faculty Practice. He serves as Medical Toxicology consultant for the Agency for Toxic Substances and Disease Registry, region 9, and the Environmental Protection Agency, region 9. Dr. Durrani has publications in basic science and public health disciplines, and has presented abstracts in neurotoxicology. Dr. Durrani’s career combines medicine with public health, allowing him to focus on individual patients while considering their population and environment. He has experience in caring for populations both domestically and internationally, having volunteered in multiple countries and as a Preventive Medicine Officer with the U.S. Army in Afghanistan. His academic interests include occupational and environmental toxicology, reproductive toxicology, pediatric toxicology and clinical pharmacology. 

Zlatnik125.jpgMarya G. Zlatnik, MD. MMS
Clinical Professor, Department of Obstetrics, Gynecology and Reproductive Sciences
University of California San Francisco
San Francisco, CA

Marya Zlatnik MD, MMS, is a professor of Obstetrics, Gynecology, & Reproductive Sciences at UCSF, and a Maternal Fetal Medicine specialist, with clinical expertise in ultrasound and the diagnosis of fetal anomalies. She has a long-standing interest in environmental toxins and their effect on pregnancy. She is a member of UCSF’s Program in Reproductive Health and the Environment (PRHE) and the  FASTEP Advisory council since 2008, as well as the associate director of UCSF’s fellowship in Maternal Fetal Medicine. Her research interests include obstetrical complications and environmental toxins in pregnancy.
Dr. Zlatnik earned her medical degree at the University of Iowa and completed a residency in obstetrics and gynecology, a fellowship in maternal-fetal medicine and a master's program in medical science at the University of Texas Medical Branch in Galveston.

Module Recording and Materials


Continuing Education

To obtain CE credit for this webcast you must first establish a login with the CDC. Click here to access the CDC Training and Continuing Education Online webpage.


CME activities with Joint Providers: This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint providership of the Centers for Disease Control and Prevention and the American College of Medical Toxicology. The Centers for Disease Control and Prevention is accredited by the (ACCME®) to provide medical education for physicians. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Regarding WC2611 - The Centers for Disease Control and Prevention designates this live educational activity for a maximum of 1.0 AMA PRA Category 1 Credits™.

Regarding WD2611 - The Centers for Disease Control and Prevention designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credits™.

CNE: The Centers for Disease Control and Prevention is accredited as a provider of Continuing Nursing Education by the American Nurses Credentialing Center's Commission on Accreditation.

This activity provides 1.0 contact hours.

CEU: The Centers for Disease Control and Prevention is authorized by IACET to offer 1.0 CEU's for this program.

CECH: Sponsored by the Centers for Disease Control and Prevention, a designated provider of continuing education contact hours (CECH) in health education by the National Commission for Health Education Credentialing, Inc. This program is designated for Certified Health Education Specialists (CHES) and/or Master Certified Health Education Specialists (MCHES) to receive up to 1.0 total Category I continuing education contact hours. Maximum advanced level continuing education contact hours available are 0. CDC provider number GA0082.

For Certified Public Health Professionals (CPH)
CDC is an approved provider of CPH Recertification Credits by the National Board of Public Health Examiners. Effective October 1, 2013, the National Board of Public Health Examiners (NBPHE) accepts continuing education units (CEU) for CPH recertification credits from CDC. Please select CEU as your choice for continuing education when registering for a course on TCEOnline. Learners seeking CPH should use the guidelines provided by the NBPHE for calculating recertification credits. For assistance please contact NBPHE at

DISCLOSURE: In compliance with continuing education requirements, all presenters must disclose any financial or other associations with the manufacturers of commercial products, suppliers of commercial services, or commercial supporters as well as any use of unlabeled product(s) or product(s) under investigational use.

CDC, our planners, presenters, and their spouses/partners wish to disclose they have no financial interests or other relationships with the manufacturers of commercial products, suppliers of commercial services, or commercial supporters with the exception of Charles A. McKay and he wishes to disclose that he is a member of the Scientific Advisory Council, Environmental Health Research Foundation (EHRF). EHRF addresses issues related to biomonitoring, a topic that is also relevant to some of the activities in the Grand Round Series that might be discussed in future sessions. EHRF receives funding from sources that includes industry. Dr. McKay has reviewed and written material for EHRF, that could create a perceived conflict of interest regarding environmental chemical exposure assessment/measurement.

Planning committee discussed conflict of interest with Dr. Charles A. McKay to ensure there is no bias.

Content will not include any discussion of the unlabeled use of a product or a product under investigational use.

CDC does not accept commercial support.

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