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ToxIC Registry Update

Several ToxIC Registry abstracts were presented at NACCT in Vancouver, and submissions are in for ASM 2018.

 Review manuscripts published in 2017

  1. Farrugia LA, Rhyee SH, Calello DP, Campleman SL, Riederer AM, Malashock HR, Pizon A, Wiegand T, Wax PM, Brent J. The Toxicology Investigators Consortium Case Registry-the 2016 Experience. Toxicology Investigators Consortium Study Group. J Med Toxicol. 2017 Aug 1. 
  2. Finkelstein Y1, Goel G, Hutson JR, Armstrong J, Baum CR, Wax P, Brent J; Toxicology Investigators Consortium (ToxIC). Drug Misuse in Adolescents Presenting to the Emergency Department. Pediatr Emerg Care. 2017 Jul;33(7):451-456. 
  3. Heise CW, Malashock H, Brooks DE. A review of vilazodone exposures with focus on serotonin syndrome effects. Clin Toxicol (Phila). 2017 Nov;55(9):1004-1007.
  4. Ho JH, Leikin JB, Dargan PI, Archer JRH, Wood DM, Brent J. Metal-on-Metal Hip Joint Prostheses: a Retrospective Case Series Investigating the Association of Systemic Toxicity with Serum Cobalt and Chromium Concentrations. J Med Toxicol. 2017 Sep 12. 
  5. Monte AA, Calello DP, Gerona RR, Hamad E, Campleman SL, Brent J, Wax P, Carlson RG; ACMT Toxicology Investigators Consortium (ToxIC). Characteristics and Treatment of Patients with Clinical Illness Due to Synthetic Cannabinoid Inhalation Reported by Medical Toxicologists: A ToxIC Database Study. J Med Toxicol. 2017 Apr 10. PubMed PMID: 28397128.
  6. Rasimas JJ, Smolcic EE, Sinclair CM. Themes and trends in intentional self-poisoning: Perspectives from critical care toxicology. Psychiatry Res. 2017 Sep;255:304-313. PubMed PMID 28601000
  7. Ruha AM, Kleinschmidt KC, Greene S, Spyres MB, Brent J, Wax P, Padilla-Jones A, Campleman S; ToxIC Snakebite Study Group. The Epidemiology, Clinical Course, and Management of Snakebites in the North American Snakebite Registry. J Med Toxicol. 2017 Oct 3. PubMed PMID:28975491
  8. Spyres MB, Ruha AM, Kleinschmidt K, Vohra R, Smith E, Padilla-Jones A. Epidemiology and clinical outcomes of snakebite in the elderly: a ToxIC database study. Clin Toxicol (Phila). 2017 Jul 13:1-5. PubMed PMID: 2870302

We have implemented the ToxIC Champions Program to enhance site coordination and communication. Many thanks to our Champions Meghan Spyres, Gillian Beauchamp, Melissa Vandenberg, and Evan Schwarz.

As a reminder, the registry is composed not only of the core data collection instrument, but of a number of prospective registries which were set up to answer compelling questions in Medical Toxicology:

  1. The Extracorporeal Therapies (ECT) Registry, PI: Joshua King
  2. Lipid Emulsion Therapy Registry, PI: Michael Levine
  3. Natural Toxins Registry, PI: Rob Hendrickson
  4. North American Snakebite Registry (NASBR), PI: Michelle Ruha
  5. New! Pediatric Marijuana and Opioid Registry, PI: Yaron Finkelstein
  6. Prescription Opioids Misuse Registry, PI: Amy Zosel

Coming soon in 2018: Quality Measure Assessment is being built to provide ToxIC the framework to track clinical performance for better third-party reimbursement of consultations. More information to follow soon.

Looking to start doing ToxIC research, or get more involved? Reach out to me, or anyone on the ToxIC leadership team: Diane Calello (

As always, all of this information and more is available on the ToxIC website: Check it out!