Society of Academic Emergency Medicine Foundation (SAEMF) / Medical Toxicology Foundation (MTF) Toxicology Research Grant
Number of Grants Available: 1
Funding Duration: 1 year
Application Deadline: August 1, 2022
Funding Period: July 1, 2023 - June 30, 2024
PURPOSE OF THE AWARD
The mission of the grant is to provide support for research proposals that advance the science of medical toxicology in emergency medicine. The goals are to foster collaboration between members of ACMT and SAEM and to advance the science of medical toxicology as it relates to all aspects of emergency medicine. Proposals that intend to collect data necessary to pursue larger projects (pilot projects) are of particular interest. The research proposals can address one or more of the following areas and topics:
- Medical toxicology practice
- Medical toxicology education (medical students, emergency medicine residents, medical toxicology residents and emergency physicians)
- Acute or chronic toxicity from pharmaceuticals and chemicals
- Envenomations and natural toxins
- Opioid-use disorders and addiction medicine
- Chemical or radiological emergency preparedness
- Global medical toxicology
The applicant must:
- Be a member in good standing of ACMT or SAEM at application deadline and during the entire award period;
- Be a physician holding an applicable terminal clinical degree (e.g., MD, DO);
- Be an emergency medicine resident, or a medical toxicology fellow, or faculty member in good standing in an Accreditation Council on Graduate Medical Education (ACGME)-approved emergency medicine residency program are also eligible for the award;
- Not have received the MTF-SAEMF Toxicology Research Grant previously.
Greater consideration for receipt of the award will be given to applicants who:
- Have demonstrated promise and success in similar projects relevant to medical toxicology or emergency medicine. Evidence of this promise may include previous participation in research activities related to these fields, peer-reviewed publications and presentations, presentations of scholarly activity at scientific meetings, and local, regional, national and international activities focused on research and education.
- Demonstrate evidence of involvement in MTF or SAEM activities and functions. Considerations in this regard include participation in ACMT and/or SAEM activities and functions (e.g., presentations and committee membership). Applicants will be scored according to their expressed and demonstrated commitment to ACMT and SAEM.
The Applicant's Host Institution
The host institution must:
- Provide adequate administrative and clerical support to the applicant and project, including but not limited to: office space, administrative support, and information systems;
- Demonstrate a track record of involvement and commitment to medical toxicology and emergency medicine research.
- Demonstrate the availability of faculty, resident and /or medical student teaching opportunities relevant to the project and applicant’s needs for the project;
THE FINANCIAL AWARD
The MTF-SAEM Foundation Toxicology Research Grant will provide up to $20,000 for an applicant’s project, contingent on the availability of funds from the two organizations. The MTF and SAEM Foundation may discontinue, postpone, or change grant funding based on the amount of funds available. The number and monetary amount of awards granted will depend on the quality of applications and status of the funds. Funds from the grant may be used for direct costs related to the project. A maximum of $1000 may be used for travel to conferences to present research findings.
Funds from the grant may not be used for faculty salary support. Statistical support costs are allowable under this grant. Indirect costs (i.e., facilities and administrative costs) are not supported by this grant. No additional costs are supported by the SAEM Foundation; any other costs are the responsibility of the applicant’s host institution. Any residual funds will be returned to SAEM Foundation at the end of the award period.
Costs included in the budget may not exceed $20,000 per year. However, in addition to the funds from this grant, the budget justification should reflect all pending and active sources of funding relevant to the project. The submission of a detailed budget and budget justification with both awarded funds and additional funds available to support the project from all sources are required as part of the application.
Failure to meet the award guidelines or inability of the awardee to complete the term of the award shall result in the return of remaining funds to SAEM Foundation.
For projects requiring the host institution’s Institutional Review Board (IRB) or equivalent approval, funds will not be dispersed until IRB approval is obtained. Award extensions may be made at the discretion of the Grants Committee on a case-by-case basis.
DURATION OF THE AWARD
The award is for one year (grant period July 1-June 30).
A progress report is due on December 1 during the grant period. The final project and financial report are due June 30th at the end of the grant period. The progress report template is available at Post Award.
At the end of the grant award year (June 30th), the awardee is expected to provide MTF and the SAEM Foundation with a final report outlining the work completed during the research project. Successful project completion will be demonstrated by at least one of the following: (1) a research abstract submitted to the ACMT, SAEM or other national meeting relevant to the project topic, and/or (2) a manuscript submitted to a peer-reviewed publication relevant to the project topic. The awardee also is expected to attend the ACMT or the SAEM Annual Meeting during their award year, preferably presenting a topic from their research.
GRANT REVIEW PROCESS
The SAEM Foundation Grants Committee is responsible for reviewing grant applications for this award and will make recommendations to the SAEM Foundation and MTF Board of Trustees. The committee uses a scoring system to judge and compare applications according to the review criteria listed below. The committee seeks to recommend applications with a high likelihood of completing an innovative, high impact project. Applications will be evaluated on several parameters:
- the scientific content of the research project, including:
- a thorough background literature review
- a clearly expressed research hypothesis
- a detailed description of study methodology including anticipated timelines
- sample size calculations (where appropriate)
- statistical analyses o anticipated challenges and mitigation strategies
- knowledge translation efforts
- budget justification
- the anticipated significance, novelty and feasibility of the project
- the qualifications of the supervisor and other team members
- the role of the applicant in the initiation, development, conduct, and reporting of the project
- the anticipated educational experience for any involved trainees
- any other support (financial or in-kind) relevant to the conduct of the research
Please contact email@example.com with any questions.
POLICIES GOVERNING THE USE OF HUMANS AND ANIMALS
If human or animal experimentation is to be performed during the period of the award, the department and institution to be used as the training site must affirm that: (1) investigations involving human subjects proposed and subsequently carried out in the application have been endorsed and approved by the IRB, or other clearly designated appropriate body, at the study site; (2) any research involving human subjects will conform ethically with the guidelines prescribed by the NIH; and (3) research involving animals will conform with the current "Guide for the Care and Use of Laboratory Animals", NIH publication, of the Department of Health and Human Services/United States Public Health Service (DHHS/USPHS), and has been approved by the Animal Care and Use Committee at the study site
INVESTIGATORY FINANCIAL DISCLOSURE POLICY/OBJECTIVITY IN RESEARCH
Applicants and institutions are required by SAEMF to comply with the USPHS regulations, Final Rule, 42 CFR Part 50, Subpart F: Responsibility of Applicants for Promoting Objectivity in Research. The applicant’s and mentor’s institution or host institution official’s signature on the signature page of the application indicates compliance that an institutional administrative process is in effect to identify and resolve conflicting financial interests of the type described in Subpart 50.604(a) with respect to all projects for which funding is sought from SAEMF.
PATENT, INTELLECTUAL PROPERTY, AND TECHNOLOGY TRANSFER POLICY
All inventions discovered or arising out of research supported in whole or in part by SAEMF, which may be used in emergency medicine research, teaching, or practice, shall be reported within one (1) year to SAEMF. "Invention" is any discovery, material, method, process, product, program, software or app (mobile, application software, web application, etc) of use, whether or not patented or patentable or copyrighted or copyrightable, that has application of value such that its use, licensing, lease, or sale can generate revenue.
If the institution receiving or disbursing SAEMF funds that supported the invention has an established and applicable patent, intellectual property, or technology transfer policy/procedure for administering inventions, SAEMF will defer to that policy. If the institution has no established and applicable patent, intellectual property, or technology transfer policy/procedure for administering inventions, SAEMF shall have the right to determine the disposition of invention rights. In such cases, SAEMF may:
- Decide that patent and copyright should be or not be filed;
- Release the invention to the inventor(s) or inventor's designee;
- Submit the invention to a qualified organization for administration and licensing;
- Determine by negotiation the fair share of royalty income to be paid to the inventor(s);
- License or make other arrangements for the application and use of the invention on an exclusive or non-exclusive, royalty, or royalty-free basis.
Kevin Baumgartner, MD
This project will be a prospective observational cohort study of the human immune response to the venom of native North American crotalids. Its objectives are to characterize the development of human anti-venom antibodies (hAVAB) in envenomated patients, and, to build a cohort of biosamples from these patients. Our research will further elucidate the pattern of development of hAVAB directed against crotalid venom, and provide a biosample cohort that will support further research into the human immune response to crotalid venom. It is anticipated that this research may lead to improved understanding of the mechanism of action of crotalid venom, and potentially to the development of novel therapeutics for crotalid evenomation.
Cynthia Santos, MD
Patrick Ng, MD
The efficacy of oral sodium thiosulfate alone has not been thoroughly evaluated. Understanding the efficacy of oral sodium thiosulfate, a more readily available xenobiotic that has been demonstrated to be safe for human use, will build upon the data from our prior experiments and be useful in the development of an oral antidote for oral cyanide poisoning.