ToxIC Core Registry
Background and Purpose
ToxIC was originally created to address the lack of accurate and reliable toxicological data on adverse effects deriving from exposures to medications, drugs of abuse, natural substances, metals, pesticides, or other chemical substances. With this goal in mind, the initial case registry created by ToxIC, deemed the Core Registry, was born. All cases entered into the Core Registry represent a patient that has been formally evaluated and treated by a medical toxicologist as part of their medical care. Toxicological data is therefore gathered by trained medical toxicology physicians who are skilled in the subtle signs of toxicity and poisoning, leading to a high quality case registry.
The ToxIC Core Registry has continued to evolve since its initiation in 2010, and has led to focused data collections on exposures including vaping, illicit drug use, adverse pharmaceutical events, snakebites, and more. Since its inception, the Core Registry has accumulated data on over 90,000 cases.
ToxIC Core Registry Annual Reports Published in the Journal of Medical Toxicology
The Core Registry collects data from participating sites with the agreement that all bedside and telehealth medical toxicology consultations will be entered. Annual reports published in the Journal of Medical Toxicology summarize the registry’s yearly data and activity. Cases were identified for inclusion in these reports by a query of the ToxIC database for any case entered from January 1 to December 31 of each year. Detailed data is collected from these cases and aggregated to provide information, which included demographics, reason for medical toxicology evaluation, agent and agent class, clinical signs and symptoms, treatments and antidotes administered, mortality, and whether life support was withdrawn.